How long does maxalon take to work

It is also activated directly by agents circulating in the blood, for example anti-cancer medicines or anaesthetics. Once activated, it sends messages to another area of the brain, the vomiting centre, which in turn sends messages to the gut, causing the vomiting reflex.

Blocking the dopamine receptors in the CTZ prevents nausea messages from being sent to the vomiting centre. This reduces the sensation of feeling sick and prevents vomiting. Metoclopramide also acts in the upper end of the digestive system, where it enhances the action of a natural chemical called acetylcholine.

This results in tightening of the muscles at the entry to the stomach, relaxation of the muscles at the exit of the stomach and increased contraction of the muscles in the stomach itself.

These actions speed the passage of food through the stomach into the intestine, which physically helps to prevent vomiting. Due to its action on the gut, metoclopramide is useful in migraine, not only for relieving feelings of sickness, but also because during a migraine attack stomach emptying is slowed, which can prevent painkillers from being absorbed.

Metoclopramide speeds up the passage of painkillers from the stomach to the intestine, from where they can be absorbed to relieve the headache. Intramuscular administration of Maxolon facilitates the absorption of a range of drugs including the absorption of aspirin in people with migraine.

Maxolon has been found useful in the management of gastric retention after gastric surgery. Maxolon may be useful in the treatment of diabetic gastroparesis of mild to moderate severity. Young Adults and Children: The use of Maxolon in patients under 20 years should be restricted to the following situations: Severe intractable vomiting of known cause. Vomiting associated with radiotherapy and intolerance to cytotoxic drugs.

As an aid to gastrointestinal intubation. You should seek medical advice in relation to medicines and use only as directed by a healthcare professional. Images are the copyright of the Pharmacy Guild of Australia. All medicines and poisons in Australia are categorised by how they are made available to the public. Medicines with a low safety risk are usually less tightly controlled than medicines with a higher safety risk. This system is called 'scheduling'. You can read more about the scheduling of medicines as well as the different scheduling categories on our Scheduling of medicines and poisons information page.

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine. If you are over 65 years of age, there may be specific risks and recommendations for use of this medicine. Please discuss your individual circumstances with your pharmacist, doctor or health professional. Take it as soon as you remember, and then go back to taking the medicine as you would normally.

Do not take a double dose to make up for the dose that you missed. Immediately telephone your doctor or the Poisons Information Centre Australia 13 11 26, New Zealand for advice, or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much Maxolon.

Do this even if there are no signs of discomfort or poisoning. Symptoms of an overdose may include drowsiness, confusion, dizziness, headache, agitation, nausea, vomiting, constipation, tremor, twitching or uncontrolled spasm of muscles. If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Maxolon. Tell any other doctors, dentists, and pharmacists who treat you that you are taking this medicine.

If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine. This medicine may cause dizziness, light-headedness, tiredness or drowsiness in some people. If you have any of these symptoms, do not drive, operate machinery or do anything else that could be dangerous.

Children should be careful when riding bicycles or climbing trees. Maxolon ampoules will be stored in the pharmacy or on the ward. Do not store Maxolon or any other medicine in the bathroom or near a sink. Do not leave it on a windowsill or in the car. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Maxolon. This medicine may have unwanted side effects in a few people.

All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects. The above list includes the more common side effects of your medicine. They are usually mild and short-lived. The above list includes serious side effects that may require medical attention. Serious side effects are rare. If any of the following happen, tell your doctor immediately or go to Accident and Emergency at your nearest hospital:.

The above list includes very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are very rare. View more information about myVMC. Please be aware that we do not give advice on your individual medical condition, if you want advice please see your treating physician.

You will generally take it for up to 5 days maximum. For migraine you will only take it when you have symptoms. You will not need to take it every day. For nausea and vomiting caused by chemotherapy or radiotherapy, take it for as long as your doctor tells you to. Talk to your doctor or pharmacist if you're unsure how long you need to take metoclopramide for.

Alcohol and metoclopramide together can make you sleep very deeply and you may have difficulty waking up. This can be very dangerous. Except for avoiding alcohol, you can eat and drink normally while taking metoclopramide.

Metoclopramide does not affect any type of contraception, including the combined pill and emergency contraception. But if metoclopramide makes you have severe diarrhoea for more than 24 hours, your contraceptive pills may not protect you from pregnancy. Find out what to do if you're taking the pill and you have diarrhoea. There's no firm evidence that metoclopramide will affect fertility in either men or women. Do not drive a car, ride a bike, use tools or machinery if metoclopramide makes you sleepy, affects your vision, or makes you feel dizzy, clumsy or unable to concentrate or make decisions.

This may be more likely when you first start taking metoclopramide, but could happen at any time for example, when starting another medicine.

It's best to wait until you know how the medicine affects you. It's an offence to drive a car if your ability to drive safely is affected. It's your responsibility to decide if it's safe to drive. If you're in any doubt, do not drive. Find more information on the law on drugs and driving on GOV. Talk to your doctor or pharmacist if you're unsure whether it's safe for you to drive while taking metoclopramide. There are some lifestyle changes that can help with feeling or being sick :.

Page last reviewed: 3 February Next review due: 3 February Metoclopramide - Brand name: Maxolon On this page About metoclopramide Key facts Who can and cannot take metoclopramide How and when to take it Side effects How to cope with side effects Pregnancy and breastfeeding Cautions with other medicines Common questions. About metoclopramide Metoclopramide is an anti-sickness medicine known as an antiemetic. It's used to help stop you feeling or being sick nausea or vomiting including: after radiotherapy or chemotherapy treatment for cancer sickness you may get with a migraine if you've had an operation at the end of life palliative care Metoclopramide comes as tablets or a liquid that you swallow.

It is only available with a prescription. Help us improve our website Can you answer a quick question about your visit today? You'll usually only take metoclopramide for a short time up to 5 days. The most common side effects are feeling sleepy drowsy and diarrhoea Avoid drinking alcohol with metoclopramide.

It will make you feel more sleepy. Brand names for combination migraine treatments include Migramax metoclopramide with aspirin , and Paramax metoclopramide with paracetamol.